Potensi Aktivitas Ekstrak Etanol Rimpang Kunyit (Curcuma longa) sebagai Antibakteri Escherichia coli

Penulis

  • Suci Wulandari Fakultas Farmasi, Institut Kesehatan Medistra Lubuk Pakam, Indonesia Penulis
  • Aminah Syarifuddin Fakultas Farmasi, Institut Kesehatan Medistra Lubuk Pakam, Indonesia Penulis
  • Cucu Arum Dwi Cahya Fakultas Farmasi, Institut Kesehatan Medistra Lubuk Pakam, Indonesia Penulis
  • Pebriani Nainggolan Fakultas Farmasi, Institut Kesehatan Medistra Lubuk Pakam, Indonesia Penulis

DOI:

https://doi.org/10.52622/jisk.v4i1.04

Kata Kunci:

Turmeric, potency, antibacterial, Escherichia coli

Abstrak

Background: Turmeric (Curcuma longa) is well known as one of the many medicinal plants in the form of rhizomes, both on a home and industrial scale. The chemical components contained in the rhizomes include fat, ascorbate, protein, starch, tannin, curcumin, flavonoids and essential oils. Turmeric is commonly used by people to reduce the frequency of diarrhoea. Apart from having chelating properties, it is also anti-inflammatory and even antibacterial. Objective: The study was directed to investigate the potential of ethanol extract of turmeric rhizomes (EERK) on Escherichia coli. Method: Dry rhizome powder was macerated using 96% ethanol, then rotary evaporated to obtain dry turmeric rhizome extract (EKRK), and divided into concentrations of 30, 40, and 50%, positive or negative control. Results: The study shows that there is an influence of EKRK concentration on the antibacterial potential of Escherichia coli. One-way ANOVA described that there was a significant difference (p < 0.010) in the use of various EKRK concentrations as inhibitors of bacterial growth and development. Antibacterial activity at 30, 40, and 50 % was 14.3, 17.5, and 19.7 mm, respectively. Conclusion: EERK has strong potential as an antibacterial for Escherichia coli.

Unduhan

Data unduhan tidak tersedia.

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Diterbitkan

2023-04-30

Cara Mengutip

[1]
Suci Wulandari, Aminah Syarifuddin, Cucu Arum Dwi Cahya, and Pebriani Nainggolan , Trans., “Potensi Aktivitas Ekstrak Etanol Rimpang Kunyit (Curcuma longa) sebagai Antibakteri Escherichia coli”, jisk, vol. 4, no. 1, pp. 20–24, Apr. 2023, doi: 10.52622/jisk.v4i1.04.

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