Toxicity of n-Hexane Juice Fraction of Kopasanda Leaves (Chromolaena odorata (L.) R.M King & H.Rob) to Shrimp Larvae Using the BSLT (Brine Shrimp Lethality Test) Method
DOI:
https://doi.org/10.52622/jisk.v1i1.6Keywords:
Kopasanda (Chromolaena odorata), n-hexane fraction, polyphenol, toxicityAbstract
Kopasanda leaf plants (Chromolaena odorata (L.) R.M.King & H.Rob) are plants commonly used as medicinal ingredients empirically. The people of East Aceh use it as a wound medicine. Preliminary tests show that the extract and its partitions have a toxic effect on shrimp larvae. In this study, the soluble extract of n-hexane was fractionated using column chromatography with isocratic mobile phase n-hexane: ethyl acetate (7: 3) and silica gel stationary phase. Analysis of the chemical content profile using thin-layer chromatography showed that there were polyphenol organic compounds. The fraction 7 obtained shows that it is toxic to shrimp larvae of Artemia salina Leach.
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