Analysis of Vitamin C Levels and Evaluation of Effervescent Tablets Mixture of Ethanol Extract of Red Guava Seeds and White Guava Seeds (Psidium Guajava L.)

Authors

  • Hendri Faisal Fakultas Farmasi, INKES Helvetia Medan Author
  • Suprianto Program Studi Farmasi, STIKes Indah Medan Author
  • Nur Aisyah Pitri Fakultas Farmasi, INKES Helvetia Medan Author
  • Sri Handayani Fakultas Farmasi, INKES Helvetia Medan Author
  • Dwi Setio Purnomo Fakultas Farmasi, INKES Helvetia Medan Author

DOI:

https://doi.org/10.52622/jisk.v3i1.40

Keywords:

Guava, vitamin C, UV spectrophotometry

Abstract

Effervescent tablets, CO2-producing tablets from the reaction of tablet constituents with their solvents. Red guava contains beta-carotene vitamin C is quite high, white guava is rich in vitamins, flavonoids, carotenoids, saponins, tannins, phenols, triterpenes, essential oils, fiber, and fatty acids. The study aimed at the comparison of vitamin C extract of red and white guava seeds (Psidium guavala. L). Powder evaluation includes flow time, angle of repose, compactibility. The evaluation of tablets included organoleptic, soluble time, weight uniformity, hardness, friability, pH, vitamin C content using UV spectrophotometry method. The results showed that the flow time test was 11.31-16 gram/second, the angle of repose was 33.02-34.92%; compactibility 7.59-16.9%; effervescent tablet preparation is round in shape, brown aroma, dark brown-brown color, slightly sweet taste, dissolving time 33.79- 89.53 seconds; hardness 4-5,4 kg; friability 0.04-0.9%; pH is close to neutral at pH 5.83-6.39; vitamin C content of red and white guava seeds were 37.86 mg/g and 42.32 mg/g, respectively. Red and white guava seed extract can be formulated into effervescent tablets and has vitamin C 0.19 – 0.28 mg/g

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References

Tanjung YP, Puspitasari I. Formulasi dan Evaluasi Fisik Tablet Effervescent Ekstrak Buah Mengkudu (Morinda citrifolia L.). Farmaka. 2019;17(1):1–14. https://doi.org/10.24198/jf.v17i1.19435

Wardani LA. Validasi Metode Analisis dan Penentuan Kadar Vitamin C pada Minuman Buah Kemasan dengan Spektrofotometri UV-Visible. [Skripsi]. Jakarta: Universitas Indonesia; 2012.

Sudewo B. Basmi Kanker dengan Herbal. Jakarta: VisiMedia; 2012.

Bakti KK. Efek Proteksi Jus Jambu Biji Putih (Psidium guajava l.) terhadap Kerusakan Histologis Mukosa Lambung Mencit yang Diinduksi Aspirin. [Skripsi]. Surakarta: Sebelas Maret University; 2010.

Djanis RL, Hanafi. Aktivitas Antioksidan Selama Pematangan Buah Jambu Biji (Psidium guajava L.). War Akab. 2009;(22):12–23.

Lynatra C, Wardiyah W, Elisya Y. Formulation Of Effervescent Tablet Of Temulawak Extract (Curcuma xanthorrhiza Roxb.) With Variation Of Stevia As Sweetener. Sanitas. 2018;9(2):72–82. https://doi.org/10.36525/sanitas.2018.9

Gunawan M, Suprianto, Samran, Fatimah C, Melani D, Sumardi. Tablet Kompresi Langsung Ekstrak Etanol Daun Salam (Syzygium polyanthum). J Indah Sains dan Klin. 2021;2(3):1–6.https://doi.org/10.52622/jisk.v2i3.31

Anggraeni E, Djamaluddin A, Ratnasari D. Pembuatan dan Uji Organoleptik serbuk Instan Mentimun (Cucumis sativus L.) sebagai Antihipertensi dan Penambahan Jeruk Nipis sebagai Rasa Khas (Citrus aurantifolia). J Holist Heal Sci. 2020;4(2):120–8. https://doi.org/10.51873/jhhs.v4i2.67

Kholidah S, Yuliet Y, Khumaidi A. Formulasi Tablet Effervescent Jahe (Z Officinale Roscoe) dengan Variasi Konsentrasi Sumber Asam dan Basa. J Sci Technol. 2014;3(3):216–29. https://doi.org/10.22487/25411969.2014.v3.i3.3325

Suprianto, Hafiz I, Faisal H, Harefa HM. Validasi Metode Penentuan Tablet Allopurinol Menggunakan Spektrofotometri Ultraviolet dalam Larutan Asam. J Kim Sains dan Apl. 2019;22(2):29–37. https://doi.org/10.14710/jksa.22.2.29-37

Kailaku SI, Sumangat J. Formulasi Granul Efervesen Kaya Antioksidan dari Ekstrak Daun Gambir. J Penelit Pascapanen Pertan. 2012;9(1):27–34. http://dx.doi.org/10.21082/jpasca.v9n1.2012.27-34

Suprianto, Syamsul D, Harfiansyah MD. Aplikasi Metode Penetapan Kadar Rutin Parasetamol PT. Kimia Farma, Tbk secara HPLC pada Sediaan Tablet Generik dan Bermerek di Medan. J Indah Sains dan Klin. 2020;2(1):1–5. https://doi.org/10.52622/jisk.v1i1.1

Arel A, Martinus BA, Ningrum SA. Penetapan Kadar Vitamin C pada Buah Naga Merah (Hylocereus costaricensis (fac weber) Britton & Rose) dengan Metode Spektrofotometri UVVisibel. Scientia. 2017;7(1):1–5.

Romantika RC, Wijana S, Perdani CG. Formulasi dan Karakteristik Tablet Effervescent Jeruk Baby Java (Cytrus sinensis L. Osbeck) Kajian Proporsi Asam Sitrat. J Teknol dan Manaj Agroindustri. 2017;6(1):15–21.

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Published

30-04-2022

How to Cite

[1]
Hendri Faisal, Suprianto, Nur Aisyah Pitri, Sri Handayani, and Dwi Setio Purnomo , Trans., “Analysis of Vitamin C Levels and Evaluation of Effervescent Tablets Mixture of Ethanol Extract of Red Guava Seeds and White Guava Seeds (Psidium Guajava L.)”, jisk, vol. 3, no. 1, pp. 1–7, Apr. 2022, doi: 10.52622/jisk.v3i1.40.

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