Antimicrobial Effectiveness of the Combination of Turmeric Rhizome Ethanol Extract (Curcuma longa L.) and Hydroxyapatite in Inhibiting the Growth of Streptococcus sobrinus
DOI:
https://doi.org/10.52622/jisk.v7i1.01Keywords:
Curcuma longa L., hydroxyapatite, antimicrobial activity, Streptococcus sobrinus, dental cariesAbstract
Background: Dental caries is one of the most prevalent oral health problems worldwide, affecting both children and adults. Streptococcus sobrinus plays a major role in caries development by fermenting carbohydrates and producing acids that lead to enamel demineralization. The use of conventional chemical antimicrobials may cause side effects, including disruption of the oral microflora and the development of bacterial resistance. Therefore, natural antimicrobial alternatives are needed. Objective: This study aimed to evaluate the antimicrobial effectiveness of a combination of ethanol extract of turmeric rhizome (Curcuma longa L.) and hydroxyapatite against Streptococcus sobrinus. Methods: This experimental study assessed various ratios of turmeric ethanol extract and hydroxyapatite for their effects on the growth of Streptococcus sobrinus using the inhibition zone method. Phytochemical screening was also conducted to identify bioactive compounds in the turmeric extract. Results: Phytochemical analysis revealed the presence of alkaloids, flavonoids, tannins, and saponins. Antibacterial testing showed inhibition zones of 10.6 mm for turmeric extract, 7.7 mm for hydroxyapatite, and 10.7 mm for the combination at a 3:1 ratio. Conclusion: The ethanol extract of turmeric rhizome, when combined with hydroxyapatite, demonstrated inhibitory activity against Streptococcus sobrinus, suggesting potential as a natural antimicrobial for dental caries prevention.
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